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Noofen tablets 250mg #20

Noofen tablets 250mg #20

Brand: Latvia
Product Code: 066
Availability: In Stock
Price: $48.00
Qty:     - OR -  
DELIVERY WITHIN 9-11 DAYS.

Noofen (Phenibut) is the drug that combines all these properties. It ameliorates memory, intellectual activity, enhances brain resistance to harmful effects.

Structure and Composition:

 
NOOFEN
 
Table. 250 mg blister, № 20
 
 Phenibut 250 mg
Other ingredients: lactose, potato starch, calcium stearate.
 
 
Pharmacological properties:
 
Noofen is a derivative of GABA and phenylethylamine (γ-amino-β-phenylbutyric acid hydrochloride). Is dominant and its antihypoxia antiamnesic action. Has tranquilizing properties, stimulates memory and learning, increases physical performance, eliminates psycho-emotional stress, anxiety, fear, and improves sleep prolongs and enhances the action of hypnotics, narcotics, neuroleptics, and anticonvulsants. Does not affect the choline-and adrenoreceptors. The drug prolongs the latency and reduces the duration and severity of nystagmus. Visibly reduces the appearance of fatigue and vazovegetativnye symptoms, including headache, a feeling of heaviness in the head, insomnia, irritability, emotional lability, enhances mental performance. Unlike drugs, under the influence of Noofena improves the higher nervous activity (attention, memory, speed and accuracy of the sensory-motor responses). In patients with asthenia and emotionally labile patients from the first days of therapy, the drug improves health, increases the interest and initiative, motivation to be active without sedation or stimulation. Found that when taking Noofena in traumatic brain injury increases the number of mitochondria in the cells of perifocal tissue and improved bioenergetic processes in the brain. If there are violations of the heart and stomach normalizes the process of lipid peroxidation.
Well absorbed after oral administration and is well into all tissues of the body, penetrates the BBB. Distributed in the liver and kidneys even, but in the brain and blood - uneven. After 3 hours, Phenibut determined in the urine, at the same time, the concentration of the drug in the brain is not reduced, it has been detected in the brain after 6 pm on the day after taking phenibut can be detected only in the urine, it is determined in the urine after 2 days after reception, but detectable amount of 5% of the administered dose. The greatest binding phenibut in the liver (80%), it is not specific. With the re-introduction of cumulation is not marked.
 
INDICATIONS:
 
reduction of intellectual and emotional activity, impaired memory, reduced concentration. Asthenic and anxious and neurotic states, anxiety, fear, anxiety, obsessive-compulsive disorder, personality disorder in children - stuttering, enuresis, teak, the elderly - insomnia, nocturnal restlessness. Prevention of stress conditions before surgery or painful diagnostic studies. Noofen used as an aid in the treatment of alcoholism and for the relief of psychiatric disorders in somatovegetativnyh abstinence syndrome. It can be taken with conventional combines detoxication agents for the treatment of alcohol and predelirioznyh delirious states. Assign well as Meniere's disease, vertigo, associated with dysfunction of the vestibular apparatus, for the prevention of motion sickness. Used in treatment of women with osteochondrosis of the cervical spine and climacteric disorders.
 
APPLICATION:
 
Noofen taken orally before meals.
Adults appoint 250-500 mg three times a day. If necessary, the daily dose was increased to 2.5 g for children aged 3-4 years are prescribed 100 mg 2 times a day, 5-6 years - 100 mg 2-3 times daily, 7-10 years - 100 mg 3-4 times a day for 11-14 years - 200 mg 2-3 times a day. Children over 14 years - adult dosage. The highest single dose: adults - 750 mg for those aged over 60 years - 500 mg for children aged up to 6 years - 100 mg, 7-10 years - 200 mg, 11-14 years - 300 mg. The course of treatment is 4-6 weeks. Noofen be combined with other psychotropic drugs, it increases its efficiency, and you can reduce the dose and other Noofena both of the drugs.
For relief of alcohol withdrawal Noofen in the first days of treatment prescribed to 250-500 mg three times a day and 750 mg at night, with a gradual reduction of the daily dose to normal adults.
To eliminate the vertigo vestibular dysfunction of infectious origin (otogenic labyrinthitis) and Meniere's disease Noofen appointed during exacerbation of 750 mg 3 times a day for 5-7 days, with a decrease in the severity of vestibular disorders - 250-500 mg 3 times day for 5-7 days and then - 250 mg 1 time a day for 5 days. With a relatively mild disease Noofen take 250 mg 2 times a day for 5-7 days, followed by 250 mg 1 time a day for 7-10 days.
To eliminate the vertigo vestibular dysfunction of the vascular and traumatic origin Noofen appoint 250 mg 3 times a day for 12 days.
For the prevention of motion sickness in sea navigation is prescribed in doses of 250-500 mg once daily for 1 hour before the expected start of roll, or when the first symptoms of motion sickness. Action Noofena with rocking increases with a higher dosage. Upon the occurrence of pronounced manifestations of motion sickness (vomiting, etc.) appointment Noofena orally ineffective even at a dose of 750-1000 mg.
For a comprehensive treatment of women with cervical osteochondrosis of the spine and climacteric disorders appoint Noofen 250 mg 3 times daily for the first 2 weeks, in the next two weeks - 250 mg 2 times a day. In the case of moderate severity vertebrogenic pain and menopausal symptoms should use Noofena 250 mg 2 times a day every day for 4 weeks of combined treatment of osteoarthritis.
If one or more in time was not accepted by the next dose, you should continue treatment at a dose previously used.
 
CONTRAINDICATIONS:
 
hypersensitivity to the drug. Acute renal failure. During pregnancy and lactation.
 
SIDE EFFECTS:
 
after the first dose of the drug or overdose drowsiness and nausea, dizziness, headache. Rare - allergic reactions (rash, pruritus).
 
Cautions:
 
Care must be taken when assigning patients with pathology of the digestive tract due to irritation Noofena. This drug is prescribed in patients with reduced doses. With prolonged use of cellular control of the blood, liver function tests performance.
Use during pregnancy is undesirable because there is insufficient evidence to support its safety.
Patients, all of whom had drowsiness, dizziness, or other disorders of the central nervous system during treatment can not drive vehicles or serve potentially hazardous machinery.
 
INTERACTION:
 
Noofen can be used with other drugs, including psychotropic drugs (tranquilizers and neuroleptics), as their effects can be synergistic.
 
OVERDOSE:
 
Noofen low toxicity, but at a daily dose of 7-14 grams with prolonged use it may have hepatotoxic effects. These doses well above the recommended (average therapeutic daily dose - 0,75-2,5 g). Only at the highest dose applied sometimes noted eosinophilia and hepatic steatosis. Using the drug at lower doses such changes were made. The clinical picture is dominated by an overdose drowsiness, nausea, vomiting, and possible development of hypotension, renal failure. If poisoning conduct gastric lavage, activated charcoal, symptomatic therapy. When complications (hypotension, renal failure) conduct additional therapy.
 
STORAGE:
 
in a dry, dark place at a temperature of 15-25 ° C.

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