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Noofen powder 100 d/op. R-RA., 100 mg/dose 1 g in Pak. No. 15 N
Manufacturer Olainfarm, JSC, Latvia
International name Phenibut
N06BX psycho-stimulant and nootropic agents
Pharmacotherapeutic group psycho-stimulant and nootropic agents. Piracetam.
Registration № UA/3773/02/01 dated 09.07.2012. Order No. 503(2) dated 09.07.2012
The drug: active substance: phenibut;
1 bag contains finebut 100 mg;
excipients: mannitol (E 421), aspartame (E 951), flavor of orange durara (including contains sucrose, esters of mono - and digler citric and fatty acids (E s)).
Dosage form. Powder for oral solution. The powder is white to light cream color; allowed blotches of yellow color.
The name and address of manufacturer
Vul. Rupco, 5, Olaine, LV - 2114, Latvia.
Pharmacotherapeutic group. Psychostimulants and nootropics. Code ATC N06B X.
Noofen® is a derivative of γ-aminobutyric acid and phenylethylamine.
The dominant action is antypatyczny and antiamnestic action. Noofen® 100 stimulates learning processes, improves memory, increases physical and mental performance. Also Noofen® has the properties of tranquilizer: eliminates emotional tension, anxiety, fear, emotional lability, irritability, improves sleep, prolongs and enhances the effect of hypnotics, narcotic, antipsychotic and anticonvulsant agents. Psychological indicators (attention, memory, speed and accuracy of sensory-motor reactions) under the influence of Noofen improved 100 contrast to the effects of tranquilizers. The drug prolongs the latency period and reduces the duration and severity of nystagmus, has an antiepileptic effect. No effect on choline - and adrenoreceptors. Noofen® 100 significantly reduces symptoms of fatigue and vasoselective symptoms, including headache, a feeling of heaviness in the head. In patients with asthenia and emotionally labile persons from the first days of therapy with Noofen 100 improves health, increases the interest and initiative, motivation without unwanted sedation or stimulation. It is established that Noofen® 100 improves bioenergetics of the brain. The drug is well absorbed after oral administration and penetrates well into all tissues of the body, it passes through the blood-brain barrier. The distribution in the liver and kidneys close to uniform, and in the brain and blood - uniform below. After 3 h, a noticeable number of entered Noofen 100 detected in the urine, at the same time, the concentration of the drug in the brain tissue is not reduced and it is found in the brain after 6 hours. The next day Noofen® 100 can only be detected in the urine; it is found in the urine after 2 days after drinking, but found the number is only 5% of the administered dose. The greatest binding of Noofen 100 occurs in the liver (80 %), it is not specific. With the re-introduction of cumulation is not observed.
Indications for use
The decline of intellectual and emotional activity, impaired memory, reduced concentration.
Asthenic and anxiety-neurotic state, anxiety, fear, anxiety.
Stuttering, enuresis, tics.
Cases of Meniere's disease in children dizziness associated with dsfunction of the vestibular apparatus; prevention of motion sickness.
Prevention of stress conditions, prior surgeries or painful diagnostic studies.
Hypersensitivity to the drug components. Acute renal failure.
The product contains aspartame, a source of phenylalanine. Its use is contraindicated in patients with phenylketonuria.
Appropriate security measures in the application.
Children with disorders of the digestive tract should be careful due to the irritant action of Noofen 100. These children designate smaller doses.
With long-term use in control of the cellular composition of blood, the liver function tests.
Use during pregnancy or breastfeeding
Not recommended Noofen® 100 during pregnancy or breastfeeding, as there are insufficient data on the use of the drug during this period.
The ability to influence the reaction rate when driving or operating other mechanisms.
Patients who, during treatment with the drug are drowsiness, dizziness, or other disorders of the Central nervous system, you should refrain from driving or operating other mechanisms.
The experience of using the drug in children under 3 years of age have not been studied.
The way of application and dose
The content of the pack dissolve in 0.5 cups of boiling water and taken orally before meals. The treatment lasts for 2-6 weeks.
Children from 3-4 years to appoint 100 mg (1 packet) 2 times per day; 5-6 years - 100 mg 3 times a day; 7-10 years - 200 mg (2 tabs 100 mg), 2 times a day; 11-14 years - 200 mg (2 tabs 100 mg) 3 times a day.
Children over 14 years recommended to administer the drug Noofen® 250 mg tablets or capsules.
The highest single dose for children under 6 years 100 mg, from 7 to 10 years - 200 mg, from 11 to 14 years of age is 300 mg.
For prevention of motion sickness are taking a single dose of the drug Noofen® 100 an hour to travel by sea, road or air transport.
Noofen® 100 can be combined with other psychotropic drugs, it increases its efficiency, it is possible to reduce the dose of the drug Noofen® 100 and other medicines taken with him.
If one or more times in advance was not accepted next dose, continue the course of treatment should be according to the previously assigned doses.
Noofen® 100 is a drug of low toxicity, only in a daily dose of 7-14 g with prolonged use it can be hepatotoxins.
These doses significantly above the average therapeutic dose according to the age of the child. Only at the highest dose applied was observed eosinophilia and fatty liver. If the drug was administered in smaller doses, such changes were not observed.
Symptoms: drowsiness, nausea, vomiting, possible development of arterial hypotension, acute renal failure.
Treatment: washing lankadeepa symptomatic.
In case of complications (hypotension, renal failure) use supportive and symptomatic measures.
After the first application of the drug may drowsiness, nausea, dizziness, headache.
Rarely, allergic reactions, including skin rash, itching).
Interaction with other medicinal products and other forms of interaction.
Noofen® 100 can be used with other drugs, including psychotropic drugs - tranquilizers and neuroleptics (the effects are mutually reinforcing).
Shelf life: 2 years.
Storage conditions: Store in a dry, dark place at temperatures not above 25 OC. Keep out of reach of children.
1 g of the drug in the laminate sachet. 15 sachets in a cardboard bundle.