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Afobazol tablets 10mg #60

Afobazol tablets 10mg #60

Brand: Russia
Product Code: 087
Availability: In Stock
Price: $22.00
Qty:     - OR -  


Afobazol ®
non appropriated
Masterlek Company owner of the registration certificate:
Shchelkovo Vitamin Factory, Inc.
Code ATX: N05BX
Composition, structure and packing
Tablets are white or white with a touch of color Valium, Valium, with chamfer.
 1 tab. contains:
Inactive ingredients: potato starch, microcrystalline cellulose, lactose, povidone, magnesium stearate.
60pcs.  - packs cardboard.
Pharmacotherapeutic group: Tranquilizer (anxiolytic)
Registration № №:
tab. 10 mg: . - LS-000 861, 03/11/05
Pharmacological action
Selective anxiolytic, not related to the class of benzodiazepine receptor agonists. Prevents the development membranozavisimyh changes GABA-receptor.
The drug has anxiolytic (protivotrevozhnoe) action and easy incentive (activated) effect. Do not have gipnosedativnym effect (sedation seen at doses of 40-50 times the ED50 for anxiolytic action).
Reducing or eliminating anxiety (concern, bad feeling, fear, irritability), tension (fearfulness, tearfulness, anxiety, inability to relax, insomnia, fear), somatic (muscular, sensory, cardiovascular, respiratory, and gastrointestinal symptoms), vegetative (dry mouth, sweating, dizziness), cognitive (difficulty concentrating, impaired memory) violations observed at 5-7 days of treatment Afobazol. Maximum effect is achieved by the end of 4 weeks of treatment and persists posleterapevticheskom period an average of 1-2 weeks.
The drug no muscle relaxant properties, negative impact on memory and attention.
Using drugs is not formed drug dependence and withdrawal syndrome develops.
Afobazol toxic (LD50 in rats is 1.1 g with 1 mg ED50).
The drug is particularly indicated for people with mainly asthenic personality traits as alarming suspiciousness, insecurity, increased vulnerability and emotional instability, tendency to emotional and stress reactions.
Cmax was 0.13 ± 0.073 mg / ml.
The average retention time of the drug in the body - 1.6 ± 0.86 h intensively distributed to well vascularised organs.
T1 / 2 was 0.82 hours
- Anxiety disorders (generalized anxiety disorder, neurasthenia, adjustment disorder).
Dosing regimen
The drug is administered orally, after a meal. Single dose of 10 mg daily dose - 30 mg (divided into 3 doses during the day). When necessary, the daily dose may be increased to 60 mg.
The duration of the course of the drug is 2-4 weeks.
Side effect
Possible: allergic reactions, hypersensitivity to the drug.
- Pregnancy
- Lactation (breastfeeding);
- The age of 18;
- Hypersensitivity to the drug.
Pregnancy and lactation
The drug is contraindicated during pregnancy and lactation (breastfeeding).
Symptoms: When a large overdose and intoxication may develop sedation and hypersomnia without manifestations of muscle relaxation.
Treatment: as emergency appoint n / a caffeine-sodium benzoate 20% solution of 1 ml 2-3 times / day.
Drug Interactions
With simultaneous use Afobazol no effect on the action of ethanol and thiopental.
With simultaneous use Afobazol potentiates the anticonvulsant effect of carbamazepine.
With simultaneous use Afobazol intensifies anxiolytic action of diazepam.
Conditions and terms
The drug should be stored in a dry, protected from light, out of reach of children, at a temperature not exceeding 25 ° C. Shelf life - 2 years.
Pharmacy purchasing terms
The drug is approved for use as a non-prescription medicines.

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