ADAPTOL Instruction for using
Adaptol (mebicar) refers to a group anxioliticeski funds. Has a mild tranquilizing effect, reduces or eliminates the feeling of worry, fear, anxiety, razdrazhitelej emotional stress. The action is not accompanied by changes in motor function (coordination of movements) and muscle relaxation, therefore adaptol is considered day tranquilizer. Has no hypnotic action, but potentiates the effects of drugs for the treatment of sleep disorders. Is membranostabilizatora, a cerebral protector and adaptogen due to their antioxidant effect (especially under stress of various origins, which is accompanied by oxidative phenomena). Has properties of antagonist-agonist adrenergic system. As a neurotransmitter - acting dopamine-positive, due to what is observed in asthenic effect of adaptol. Relieves withdrawal symptoms after cessation of Smoking.
The oral bioavailability of 80%. The blood is associated with eritrotsitami (40% of the administered dose) – most of the drug not bound to proteins and circulates freely, getting through different membranes. Cmax in the serum observed after 0.2 hours after oral administration, the plateau of action of 3-4 hours, after which the concentration of the drug is gradually reduced. Is eliminated from the body by the kidneys, accumulation does not occur, and not biotransformation.
Indications for use
• Symptoms of neurosis, neuroses (emotional instability, fear, irritability, anxiety);
• in complex therapy with the goal of relief of somatic and vegetative, neurological adverse side-effects of neuroleptics, also improves the overall tolerability of this group of drugs;
• pain in the heart, not associated with angina;
• improvement of the menopause, premenstrual syndrome (reduces the severity of vegetative manifestations);
• oxidative stress of various etiologies as an adaptogen and a cerebral protector;
• comprehensive treatment of nicotine dependence (reduces the craving for Smoking).
Method of application
Tablets administered orally, regardless of the time of reception of food. Appointed 300-500 mg of adaptol 2-3 R/s. the Maximum single dose – 3 g. the Maximum daily dose – 10 g. Duration of treatment from 2-3 days to 3 months, determined on an individual basis. In Pediatrics can be used with 10 years. The children used a dosage of 300-500 mg 3 R/S. In the treatment of nicotine addiction adaptol use 0.6-0.9 g 3 R/s every day for 5-6 weeks.
Adaptol patients is well tolerated. Rarely-allergic reactions, in the case of high doses – dyspepsia (the drug in this case, stop). Very rare – hypotension and hypothermia (usually pass on their own).
Individual hypersensitivity to the components adaptol.
Has good penetration into all tissues of the body. Clinical studies on the use of adaptol in pregnant and lactating women were not conducted. Not recommended for pregnant and lactating mothers.
Combined with tranquilizers group of benzodiazepines, antidepressants, hypnotics, psychostimulants and neuroleptics.
Has no toxic properties in overdose. In case of overdose very high doses of washed stomach and appoint detoxifying tools.
White tablets valium forms, with valium and chamfer 300; 500 mg, 20 pieces in a contour package.
In a place inaccessible to children at temperature 15 - 25° C. shelf Life – 4 years.
Active substance mebicar (0,3 or 0,5 g per tablet).
Other ingredients: calcium stearate, methylcellulose.