Mucosat NEO 200mg 10 ampules 2ml (58 USD) - PayPal accepted.
Mucosat NEO 200mg 10 ampules 2ml - Miscellaneous

Mucosat NEO 200mg 10 ampules 2ml - Miscellaneous

Brand: BELMEDPREPARAT, Belorussia
Product Code: 306
Availability: In Stock
Price: $58.00
Qty:  
DELIVERY TIME: 9-12 DAYS.
MUCOSAT NEO
Instruction for use
 
Composition:
 
active substance: 2 ml (ampoule) contains chondroitin sulfate in terms of 100% substance 200 mg.
 
excipients: benzyl alcohol, water for injections.
 
Dosage form. The solution for injection.
 
Pharmacotherapeutic group. Means affecting the musculoskeletal system.
 
ATC code M 01A X 25
 
Clinical features.
 
Indications. Degenerative-dystrophic diseases of joints and spine (primary osteoarthritis between vertebral osteochondrosis, osteoarthritis), osteoporosis, parodontopathy, fractures (for faster callus formation), and also to treat the effects of operations on the joints.
 
Contraindications. Individual hypersensitivity to any component of the drug, Shilonite to bleeding, thrombophlebitis, renal failure, pregnancy, lactation.
 
Method of application and doses. The drug is administered to adults intramuscularly 1 ml every other day. In case of good tolerability, increase the dose to 2 ml starting with the fourth injection. Treatment – 25-35 injections. Repeated courses – 6 months.
 
Adverse reactions. In applying the drug in individuals with increased hypersensitivity to the drug possible violations:
 
the immune system: allergic reactions, anaphylactic shock, angio neurotic edema;
 
the skin and subcutaneous tissue: skin rash, itching, erythema, urticaria, dermatitis, alopecia. 
 
At the site of injection it is possible redness and itching.
 
Possible gastrointestinal disorders: nausea, vomiting, abdominal pain, flatulence, dyspepsia.
 
Other: violations of the organs of vision, keratopathy, dizziness, peripheral edema. 
 
Overdose. At present, the phenomena of overdose when using the drug Mucosal neo was not reported. However, we can assume that when exceeding the daily dose may increase the detection of side effects of the drug. Treatment is symptomatic.
 
Use during pregnancy or breast-feeding. Not to use during pregnancy and lactation.
 
Children. There is no experience of using the drug at children.
 
Features of the application. To achieve a stable clinical effect must be at least 25 injections of the drug. The effect persists for many months after treatment. To prevent relapses use repeated courses of treatment. It is recommended that increased doses under medical supervision for patients with excess body weight, peptic ulcer of the stomach or canadacipro intestine, while diuretics, and at the beginning of treatment when the need to accelerate clinical response.
 
In case of allergic reaction or haemorrhage treatment should be discontinued.
 
The ability to influence the rate of reaction at management of motor transport or operating other mechanisms. During application of the drug there are no restrictions regarding the management of vehicles and complex mechanisms. 
 
Interaction with other medicinal products. While the use of glucocorticosteroids and non-steroidal anti-inflammatory drugs chondroitin sulfate can reduce the need for them, as well as pain medicine. Detect a synergistic effect when applied simultaneously with glucose Minh and other chondroprotectors. The effectiveness of the treatment increases with the enrichment of the diet with vitamins a and C, and salts of manganese, magnesium, copper, zinc and selenium.
 
When taking concomitantly with acetyl salicylic acid or with other anticoagulants or antiplatelet agents is recommended to monitor blood clotting.
 
The pharmacological properties.
 
Pharmacodynamics.
 
The main active ingredients of the drug-sodium salt of chondroitin sulfate A and C (average molecular weight of 11,000 daltons). Chondroitin sulphate – high molecular weight mucopolysaccharide. It is a major component of proteoglycans, which together with collagen fibers form cartilage matrix.
 
The drug slows down the process of degeneration and stimulates the regeneration of cartilage tissue, has chondroprotective, anti-inflammatory, analgesic effect. Replaces chondroitin sulfate articular cartilage, cataloni pathological process. Inhibits the activity of enzymes that cause degradation of articular cartilage: inhibits metalloproteinase, namely leukocyte elastase. Reduces activity of hyaluronidase. Partially blocks the release of free oxygen radicals; contributes to the blocking of chemotaxis, antigenic determinants. Stimulates the production of proteoglycans by chondrocytes. Affects calcium and phosphorus metabolism in the cartilage tissue. Allows you to restore the mechanical and elastic integrity of the cartilage matrix. Anti-inflammatory and analgesic effects are achieved due to emission reduction in synovial fluid mediators of inflammation and pain factors through synoviitis and macrophages of the synovial membrane as well as inhibition of secretion of leukotrien and prostaglandin E.
 
The drug helps to restore the joint capsule and cartilage surfaces of joints, prevents compression of the connective tissue, acts as a lubricant of articular surfaces, normalizes the production of synovial fluid, improves joint mobility, reduces pain intensity, improves quality of life.
 
Mucosal neo slows down bone resorption and reduces the loss of calcium, accelerates bone tissue restoration.
 
After intramuscular administration of chondroitin sulfate penetrates into synovial fluid. The maximum concentration in synovial fluid is achieved in 4-5 hours after the injection. Excreted from the body within 24 hours. Eliminated primarily by the kidneys.
 
Pharmacokinetics.
 
After intramuscular administration of chondroitin sulfate penetrates into synovial fluid. The maximum concentration in synovial fluid is achieved in 4-5 hours after the injection. Excreted from the body within 24 hours. Eliminated primarily by the kidneys.
 
Pharmaceutical characteristics.
 
Basic physical and chemical properties:clear colorless or slightly yellowish liquid with odor of benzyl alcohol.
 
Incompatibility. 
 
No incompatibilities are not documented since the use of chondrotin sulfate (1960), however, you should avoid mixing solutions of high molecular weight polysaccharides (including chondrotin sulfate) with solutions of other drugs.
 
The expiration date. 2 years. Never use the medicine after the expiry date
 
The storage conditions. Store protected from light place, at temperature not above 20 0C.
 
Keep out of reach of children
 
Packing. 2 ml in ampoules. 5 ampoules in a contour packing. Two blisters per cardboard pack.

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