Combined contraceptives, including the estrogen component (ethinyl estradiol) and a progestogen (desogestrel). The mechanism of action is associated with inhibition of the production of gonadotropins (FSH and luteinizing hormone) by the pituitary gland, which hinders ovulation and increase the density of cervical mucus, which inhibits sperm entry into the uterus.
Indications for use
- treatment of menstrual disorders such as dysmenorrhea, PMS, dysfunctional uterine bleeding.
Method of application
You should start taking the drug Regulon from the first day of the menstrual cycle, without the use of additional contraceptive methods. If the first appointment Regulon accounts for 2-5 days of the menstrual cycle, contraception other methods, for at least a week. If since the beginning of the cycle has been more than 5 days, the reception of a Regulon should start with the next cycle.
The drug is taken 1 tablet 1 time a day, preferably at the same time, after taking 21 pills, need a break during the week, during which comes menstrualnopodobnoe reaction. After a week start to receive a new package of the drug Regulon, even if the bleeding has not stopped yet.
After birth, the drug can only when the woman is not breastfeeding. Start the drug with a 21 day postpartum period. If childbirth has had a sexual encounter, it is necessary to postpone taking the drug before menstruation. When taking the first pill Regulon after 21 days postpartum, additional contraceptive for 7 days.
When switching from another oral contraceptive, it is recommended to start taking the drug Regulon the next day after taking all the pills from the previous package of contraceptive.
If you need to delay the onset of the next menstrual period should begin taking pills from the next pack without a break of one week.
Gastrointestinal: nausea, vomiting, rarely - abnormal liver function.
From the reproductive organs and the reproductive system: intermenstrual bleeding, amenorrhea, disorders of the normal microflora of the vagina, changes in vaginal secretions, decreased libido, feeling of discomfort in the breast. Very rarely the growth of uterine fibroids.
From the circulatory system: increased blood pressure, very rarely thrombosis and embolism of different localization.
CNS: frequent mood swings, depression, headache, usually migrenepodobna character.
From the endocrine system: the body weight increase.
Other: rash, erythema nodosum, discomfort when wearing contact lenses, the development of jet SLE.
- hypersensitivity to any component of the drug;
- pregnancy or breast-feeding;
- severe liver disease, functional hyperbilirubinemia (Rotor syndrome and Dubin-Johnson), a pregnant jaundice in the anamnesis;
- family forms of hyperlipidemia;
- arterial hypertension-severe or moderate severity;
- thrombosis or embolism in anamnesis;
- herpes of the 2nd type;
- bleeding from the genital tract of unknown etiology;
- presence of estrogen-dependent tumors or suspicion on them;
- severe forms of diabetes and also gestational diabetes;
- presence of disorders of the coagulation system.
The state of pregnancy is an absolute contraindication to the drug.
Do not use concurrently with antibiotics (especially ampicillin, rifampicin, tetracycline), since it is possible to break cycles and reduce the contraceptive effect. If the intake of these antibiotics are necessary, you may need to use additional methods of contraception. It is also possible to decrease the effect of contraception and the violation of the cycle, when taking barbiturates, some antispasmodics, antidepressants, laxatives.
When combined with anticoagulation requires additional monitoring of prothrombin time and adjustment of anticoagulant dose.
Do not combine with hepatotoxic agents because of increased risk of complications.
Overdose symptoms: severe headache, dyspepsia, cramps in the calf muscles. Therapy is only symptomatic, as no specific antidote.
Tablets, film-coated, 21 tablets in the package.
Keep at temperature not exceeding 30 degrees Celsius.
Ethinyl estradiol - 0.03 mg .
Desogestrel - 0.15 mg .
Excipients: magnesium stearate, alpha tocopherol, silica colloidal anhydrous, povidone, potato starch, lactose monohydrate, propylene glycol, macrogol, hypromellose, stearic acid.
The appointment of a Regulon occurs after a thorough examination and medical history, in order to exclude the presence of diseases, which may worsen while taking the drug.
With the deterioration of liver function tests (transaminases, bilirubin), the drug should be discontinued immediately.
In the first months of taking the drug, you may experience intermenstrual bleeding, but these symptoms do not require discontinuation of the drug. If they continue more than three months need a more detailed examination.
The risk of thromboembolic complications increases with Smoking, so women taking Regulon, it is recommended to completely give up cigarettes.
With vomiting or diarrhoea, the contraceptive effect of the drug can be reduced, so it is better to use additional methods of contraception.
If you are planning a pregnancy, the reception of a Regulon should be stopped at least 3 months.
If the second month of taking the drug is not occurs menstrualnopodobnoe reaction, pregnancy must be excluded.
Breastfeeding Regulon is not assigned, so the drug can lead to reduced lactation.
If taking the pill is missed, you should take the pill that was skipped, and continue taking the drug under the scheme. If the missed pill was adopted within 36 hours after the previous, additional contraceptive measures are not needed.
Teratogenic effect of the drug has not been proven, so the pregnancy was on the background of the reception of the Regulon does not require interrupts.