basic physical and chemical properties: almost clear colorless solution with mint flavor
composition: 1 ml of product contains: acetyl cysteine – 10 mg, tuaminoheptane sulphate – 5 mg, excipients: benzalkonium chloride, metalger cellulose, disodium edetate, sodium dihydro phosphate monohydrate, disodium phosphate dodeca hydrate, ditorial, sorbitol 70%, mint flavor, ethanol 96%, sodium hydroxide, water for injections.
Form of issue. Nasal spray.
Pharmacotherapeutic group. Drugs used in diseases of the nasal cavity. ATC R01A IN 08.
The pharmacological properties.
The drug has mucolytic, decongestant action.
Acetyl cysteine, a part of the drug, promotes more rapid liquefaction of mucous and mucopurulent secretions, by breaking the disulfide nor the ties of the glycoproteins of mucus. Acetyl cysteine has anti-inflammatory effect through a mechanism of inhibition of chemotaxis of leukocytes. Acetyl cysteine has antioxidant properties.
Tuaminoheptane sulfate, simpatomimeticski Amin, the local application of vasoconstrictor effect without systemic action, eliminates edema, hyperemia of the mucous membrane.
In the treatment of inflammatory processes in the nasal cavity and paranasal sinuses mucolytic and reparative action of acetyl cysteine supplemented vasoconstrictor effect tuaminoheptane sulfate, which helps to eliminate edema. Due to the effects of the drug achieved a quick healing of the mucosa of the nasal passages and reduce symptoms of the inflammatory process.
The local application of the drug its component ingredients do not have systemic action.
Indications for use. Acute and sub acute coryza with profuse Muco-purulent exudate, chronic rhinitis, vasomotor rhinitis, sinusitis.
Method of application and doses. The drug is administered into the nasal cavity in the form of an aerosol using a special spray.
Adults: 2 dose aerosol (2 pressing the valve) in each nostril 3-4 times a day.
Children: 1 dose aerosol (1 pressing the valve) in each nostril 3-4 times a day.
The course of treatment should not exceed 7 days.
Before the using the aerosol:
Remove the cap from the bottle with the solution.
Remove the protective cap from the dispenser.
Attach to the dispenser bottle.
Remove the cover from the dispenser.
Activate the spray by pressing.
Side effects. Frequent intake of the drug in very high doses can cause side effects such as tachycardia, tremors, hypertension, disorders of urination. There may be dryness in the nose and throat, inflammation of the sebaceous glands. Adverse events were spontaneously after cessation of treatment.
Contraindications. Rinofluimucil is contraindicated in case of hypersensitivity to one of components of the drug, with closed-angle glaucoma, gpartition. The drug should not be used during treatment and for 2 weeks after treatment with antidepressants (MAO inhibitors).
Overdose. Not described. However, when this situation occurs (for example, if a child accidentally ingested a large dose) may develop as Central nervous system depression with sedation, and with the emergence of hypertensive crisis, especially in children. These reactions, caused by symptoms ethical vasoconstrictor require immediate appropriate medical treatment.
Features of the application. Be wary appoint drug in patients with arterial hypertension: treatment should be under medical supervision.
The use of the drug during pregnancy and lactation is possible only in case of extreme necessity and under medical supervision.
The drug must be cautiously used in children. No experience of the drug to children under 2 years of age, with asthma, adults suffering from prostatic hyperplasia.
Prolonged use of medicines containing vasoconstrictors, can change the normal function of the nasal mucosa and paranasal sinuses, and cause addiction to the drug.
Rinofluimucil does not affect the ability to drive vehicles and work with complex mechanisms.
Interaction with other medicinal products. Rinofluimucil incompatible with MAO inhibitors and tricyclic antidepressants. Not recommended simultaneous application Rinofluimucil with antihypertensive drugs – possible attenuation of the antihypertensive effect.
Shelf life and storage conditions. Shelf life – 2.5 years. After opening the bottle contents should be used within 20 days. Keep at temperature +15⁰ - +25⁰ C and out of reach of children.
Packing. Aerosol 10 ml in vial № 1 in set with a sprayer.