Cordiamin 25% 2ml 10 ampules (12 USD) - PayPal accepted.
Cordiamin 25% 2ml 10 ampules - Сolds and upper respiratory infections

Cordiamin 25% 2ml 10 ampules - Сolds and upper respiratory infections

Brand: Ukraine
Product Code: 243
Availability: In Stock
Price: $12.00
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DELIVERY TIME: 9-12 DAYS.
CORDIAMIN
Instruction for use
 
Pharmacological action
The drug group of analeptics, Central nervous system stimulants, non-selective actions. Is analeptic with a mixed mechanism of action, in addition to stimulation of the Central nervous system also stimulates the chemoreceptors. Acts primarily on the brain, particularly the respiratory and vasomotor centers in the medulla oblongata. The drug facilitates the process of nerve impulse transmission between neurons thereby increasing the excitability and sensitivity of the respiratory center to the natural stimuli (such as carbon dioxide). The drug also slightly inhibits the processes of inhibition in the brain, contributes to a longer pulse manifestation aftereffect. By stimulating vasomotor center increases peripheral vascular resistance, resulting in an overall increase in blood pressure. The drug has no direct action on the heart.
 
By stimulation of chemoreceptors located in the carotid sinus the drug promotes the increase of the respiratory movements. Thus, it appears peripheral action kordiamin differs from other analeptics.
Pharmacological properties the drug is an antagonist of substances having narcotic effects, including anesthetic and hypnotic drugs, and can be used in cases of poisoning with these drugs.
The drug kordiamin leads to more frequent respiratory movements, eliminates shallow breathing, making it deeper, normalizes blood pressure, facilitates the return of clear consciousness.
The drug is well absorbed regardless of the route of administration. After injection, the effect occurs within 1-3 minutes after oral after 10-15 minutes. The effect lasts after intravenous administration of 1-1,5 hours after intramuscular – 2 to 3 hours after oral for no longer than 3-4 hours. In the liver is formation of inactive metabolites excreted by the kidney.
 
Indications for use
Collapse.
Asphyxia, including asphyxia of newborns.
The shock of different etiologies.
Poisoning by hypnotics, narcotic drugs, barbiturates and other substances depressing the Central nervous system.
Violation of blood circulation in infectious diseases.
Circulatory disorders of non-infectious origin, including chronic lower vascular tone.
Respiratory failure.
Faint.
 
Method of application
Adults appoint 15-40 drops 2-3 times daily or 1-2 ml subcutaneously/intravenously/intramuscularly 2-3 times a day.
Children administered drops in the number of years (the number of drops equal to the number of years of life) 2-3 times daily or 0.1-0.75 ml depending on the age subcutaneously/intramuscularly/intravenously 2-3 times a day.
The highest single dose for adults - 2 ml daily – 6 ml. if poisoning drugs may be introduced to 5 ml of kordiamin. 
Injected intravenously very slowly.
Drops take with or without food.
To reduce pain possible prior administration of procaine.
 
Side effects
By facilitating neuronal transmission and longer pulse aftereffect of the drug can cause seizures, often clonic nature with increasing doses may cause convulsions klonico-tonic type. 
In addition, possible side effects such as:
Anxiety.
Twitching of the facial muscles.
Redness of the face and upper body.
Nausea, vomiting.
Soreness at the injection site.
Allergic reactions, including itching, rash, hives.
 
Contraindications
Individual hypersensitivity to the drug. 
The predisposition to convulsions, convulsive syndrome in history.
Epilepsy, epileptic seizures in history.
Pregnancy and lactation.
Hyperthermia in children.
 
Pregnancy
There is no reliable data on the safe use of drugs during pregnancy and lactation. It is not recommended to use this drug during pregnancy and lactation.
 
Drug interactions
The drug enhances the effect of antidepressants and drugs that stimulate the Central nervous system.
The effect of kordiamin reduced when taking derivatives fenotiazina, funds for General anesthesia, para-amino salicylic acid.
The drug is able to reduce the action of hypnotics, narcotics, ANTIEPILEPTICS, anxiolytics, antipsychotics.
Convulsive action kordiamin enhances the reception of reserpine.
 
Overdose
In case of overdose, patients present development tonicclonic seizures, excitation, high blood pressure. Shown intravenous aminophylline.
 
Release form
Solution for injection in ampoules of 1 or 2ml, 10 ampoules in a cardboard box.
The solution for oral administration via 30ml vial, 1 vial in a carton box.
 
Storage conditions
Store in a protected from direct sunlight place at a temperature not exceeding 25 degrees Celsius.
Shelf life – 3 years.
 
Synonyms
Cordoned, nicetamide.
 
Composition
1 ml of solution for injection contains:
Nicetamid – 0.25 g.
Auxiliary substances.

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