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Information about the drug, given in this section is intended for medical and pharmaceutical professionals and should not be used for self-treatment. Information given to familiarize with the basic properties of the drug and cannot be considered as official.
MANUAL for medical use of the drug CORVALMENT®
active substance: solution of menthol in mentilovom broadcast izovalerianovoy acid;1 capsule contains solution of menthol in mentilovom broadcast izovalerianovoy acid 100 mg;excipients: gelatin, glycerin, methyl parahydroxybenzoate (E 218), parahydroxybenzoate (E 216)
Soft capsules.Main physico-chemical properties: capsules spherical or spherical shape, with a seam, colorless or slightly yellow to light brownish-yellow color, filled with a transparent colorless or yellowish oily liquid with a smell of menthol.
Pharmacotherapeutic group. Cardiac therapy.
Code ATX С01Е H.
The drug has a calming effect on the Central nervous system and has a moderate reflex vasodilator (koronaroliticescoe) effect by reflex irritation of sensory nerve ("cold") receptors of the mucous membrane of the oral cavity. Stimulation of the receptor accompanied by the induction of the release of endorphins, enkephalins, dynorphins and other peptides, histamine, kinins, which play an important role in the reduction of pain, normalization of vascular permeability and regulation of other important mechanisms functioning of the cardiovascular and nervous systems.
With sublingual application Corvalment® absorbed by the mucous membrane of the oral cavity. The therapeutic effect occurs after approximately 5 minutes.After suction biotransformiroetsa in the liver and excreted in the urine in the form of glucuronides.
Clinical features.Testimony.– Angina mild; – sea and air sickness;– hysteria;– neurosis;– headache associated with taking nitrates.
Contraindications.Hypersensitivity to the drug.Severe hypotension; acute myocardial infarction.
Interaction with other medicinal products and other forms of interaction.
Corvalment® enhances the sedative effect of psychotropic drugs, opioid analgesics, alcohol and drugs for anesthesia during their concomitant use.May potentiate the action of antihypertensive drugs in their simultaneous application with the drug Corvalment®.Corvalment® reduces the severity of headaches due to nitrates.
Features of the application.
In cases where the pain in the heart area does not disappear after the drug administration, it is necessary to consult a doctor to exclude an acute coronary syndrome.The drug does not contain sugar and it can be applied to patients with diabetes.Use during pregnancy or breast-feeding.The use of the drug during pregnancy or breastfeeding is possible if, in the opinion of the physician, the expected benefits to the mother outweighs the potential risk to the fetus/baby.The ability to influence the reaction rate when driving motor transport or operating other mechanisms.Care should be taken in the first hours after drug administration in the management of vehicles or work requiring increased attention, because of possible side effects (dizziness and drowsiness).
Method of application and doses.
The capsule is kept in the mouth (under the tongue) until it dissolves completely. For faster effect can be crushed capsule teeth.Single dose for adults – 1 capsule (100 mg). Maximum daily dose of 6 capsules (600 mg).Duration of treatment – 7 days.Children.Experience in the use of medicines for the treatment of children there.
Symptoms: headache, nausea, agitation, disruption of the heart, lowering blood pressure, CNS depression, hypersensitivity reactions to components of the drug (angioedema, hives, itching, rash).Treatment: cancel the drug, symptomatic therapy.
Prolonged use can occasionally experience mild nausea, abdominal discomfort, watery eyes, dizziness, transient hypotension, drowsiness, which quickly disappear.May develop allergic reactions, including angioedema, urticaria, rash, pruritus. Parahydroxybenzoate and methyl parahydroxybenzoate included in the composition of the drug, can cause allergic reactions (possibly delayed).
The expiration date.
2 years.The storage conditions.Store in original container at temperature not exceeding 25 OC.Keep out of reach of children.Packing.10 capsules in blisters.10 capsules per blister; 3 blisters in a pack.