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Europenem (Meropenem) Powder for solution 500 mg 10 bottles

Europenem (Meropenem) Powder for solution 500 mg 10 bottles

Brand: Euro Lifecare
Product Code: 165
Availability: In Stock
Price: $245.00
Qty:     - OR -  

Information about the druggiven in this section is intended for medical and pharmaceutical professionals and should not be used for self-treatment. Information given to familiarize with the basic properties of the drug and cannot be considered as official.


Composition.Active substance: meropenem;1 vial contains Meropenem trihydrate equivalent to Meropenem anhydrous 500 mg or 1.0 g;excipient: sodium carbonate monohydrate equivalent to anhydrous sodium carbonate.|waterless|

Dosage form. Powder for solution for injection|Intro|.

Pharmacotherapeutic group. Antibacterials for systemic use.Beta-lactam antibiotics. Carbapenems. ATC code J01D H02.

Indications: Treatment of infections caused by sensitive bacteria Meropenem:• pneumonia, including hospital;• urinary tract infection;• intra-abdominal infections;• gynaecological infections such as endometritis;• infections of skin and soft tissues;• meningitis;• septicemia;• empirical therapy for suspected bacterial infection in adults with febrile neutropenia, as mono therapy or in combination with antiviral or antifungal medications.Propene applied as a mono therapy or in combined treatment with other antimicrobial agents in the treatment field, microbial infections (e.g., cystic fibrosis, chronic infections of the lower respiratory tract).

Contraindications.Hypersensitivity to the drug.Children up to age 3 months.Children with disorders of the liver and kidneys.

Method of application and doses.

Adults. The dosage and duration of therapy shall be established depending on the type and severity of infection and condition of the patient.The recommended daily dose is:In the treatment of pneumonia, urinary tract infections, gynecological infections such as endometritis, infections of skin and soft tissues – 500 mg every 8 hours Propname.In the treatment of nosocomial pneumonia, peritonitis, suspected infections in patients with neutropenia and septicaemia Propname 1000 mg every 8 hours.In cystic fibrosis the recommended dose is 2 g every 8 hours.In meningitis the recommended dose is 2 g every 8 hours.As with other antibiotics, should be especially cautious when using Meropenem as a mono therapy in critically ill patients with known or suspected Pseudomonas aeruginosa infection of the lower respiratory tract.In the treatment of Pseudomonas aeruginosa infection should regularly carry out sensitivity test.The dosing regimen for adult patients with impaired renal function.In patients with creatinine clearance below 51 ml/min the dose should be reduced as shown below:Creatinine clearance (ml/min) Dose (based on unit doses500 mg, 1 g, 2 g) Frequency 26 - 50 one unit dose every 12 hours 10 - 25 half unit dose every 12 hours < 10 half unit dose every 24 hours Propene excreted by hemodialysis; if you need long-term treatment Propaneman are advised to enter unit dose (depending on the type and severity of infection) at the end of the hemodialysis procedure to restore therapeutically effective plasma concentrations.There is no experience of using Propname in patients on peritoneal dialysis.

Dosage for patients with hepatic insufficiency. For patients with hepatic impairment dose adjustment is not required.

Elderly patients. For elderly patients with normal renal function or creatinine clearance values above 50 ml/min dose adjustment is not required.

Children. For children aged 3 months to 12 years the recommended dose is 10 - 20 mg/kg every 8 hours depending on the type and severity of the infection, sensitivity of the pathogen and condition of the patient. In children weighing more than 50 kg, use adult dose.For children aged 4 years to 18 years with cystic fibrosis, but also for the treatment of acute chronic infections of lower respiratory tract using doses in the range of 25 - 40 mg/kg every 8 hours. In meningitis the recommended dose is 40 mg/kg every 8 hours.
The method of application. Shake before use prepared solution. You can inject Europenem inside venous bolus for about 5 min or into a venous infusion for about 15 - 30 minutes.Propenes for use inside venous bolus to be dissolved in sterile water for injection (5 ml per 250 mg Meropenem), resulting in a concentration of 50 mg/ml. the Prepared solution is clear and colourless or pale yellow.Propene for internally-venous infusion can be prepared using a compatible infusion fluids (50-200 ml). Propene compatible with such liquids for infusions: 0.9% sodium chloride solution; 5 % or 10 % glucose solution; 5 % glucose with 0.02 % sodium bicarbonate; 5 % glucose with 0.9% sodium chloride; 5 % glucose with 0.225 % solution of sodium chloride; 5 % glucose with 0.15 % potassium chloride; 2.5% or 10 % solution of mannitol.
Adverse reactions. Europenem usually well tolerated. Adverse reactions rarely require cessation of treatment.
Overdose. Side effects after overdose correspond to characteristics of adverse reactions. Treatment is symptomatic; haemodialysis.
Use during pregnancy or breast-feeding. Propene should not be used during pregnancy and lactation, except cases when expected benefit for mother exceeds potential risk for fetus or child.In each case, the drug should be used under the direct supervision of a physician.For the period of treatment should refrain from breastfeeding.
Children.The drug is not administered to children under the age of 3 months and children with disorders of the liver and kidneys.Experience of use in children with neutropenia or primary or secondary immunodeficiency is absent.
Pharmaceutical characteristics. Basic physical and chemical properties: white, slightly yellowish powder.
Incompatibility.Propene should not be mixed or added to other drugs.As the solvent, use only medicines that are specified in the section "Method of administration and doses".
Shelf life. 3 years.
Storage conditions.Store in a protected from light place at temperature not exceeding 30 °C.Keep out of reach of children.


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