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Avelox 400 mg 5 tablets

Avelox 400 mg 5 tablets

Brand: Bayer AG, Germany
Product Code: 164
Availability: In Stock
Price: $43.50
Qty:     - OR -  
DELIVERY WITHIN 9-11 DAYS.

Information about the druggiven in this section is intended for medical and pharmaceutical professionals and should not be used for self-treatment. Information given to familiarize with the basic properties of the drug and cannot be considered as official.

Avelox ® tablets

Dosage form: tablets covered with a film cover

Composition: In 1 tablet contains:The active ingredient moxifloxacin hydrochloride 436,8 mg equivalent to 400,0 mg moxifloxacin.

Excipients: microcrystalline cellulose (136 mg), croscarmellose sodium (32 mg), lactose monohydrate (68 mg), magnesium stearate (6.0 mg), shell film - polymer (9.0 to 12.6 mg), dye iron oxide red (0,3 - 0,42 mg), macrogol 4000 (3,0 - 4,2 mg), titanium dioxide (2,7 - 3,78 mg).

Description: Pink frosted oblong biconvex, bevelled tablets, film-coated, engraved "BAYER" on one side and "M400" on the other side.

Pharmacotherapeutic group: antimicrobial agent - fluoroquinoloneCode ATX: [J01MA14]

INDICATIONS FOR USE Infectious-inflammatory diseases caused by sensitive to moxifloxacin microorganisms:

• Acute sinusitis,• Exacerbation of chronic bronchitis,• Uncomplicated infections of skin and subcutaneous structures,• Community-acquired pneumonia, including community acquired pneumonia caused by strains of microorganisms with multiple antibiotic resistance*,• Complicated infections of skin and subcutaneous structures (including the infected diabetic foot), • Complicated intra-abdominal infections, including polymicrobial infections, including intra-abdominal abscesses,• Uncomplicated inflammatory disease of the pelvic organs, including salpingitis and endometritis).*Streptococcus pneumoniae with multiple resistance to antibiotics include strains resistant to penicillin, and strains resistant to two or more antibiotics of groups such as penicillins (if MIK ≥2 mg/ml), cephalosporin II generation (cefuroxime), macrolides, tetracyclines and trimethoprim/sulfamethoxazole. You must take into account the existing official guidance on the rules of application of antibacterial agents.

CONTRAINDICATIONS

• Hypersensitivity to moxifloxacin, to other hinolonam or any component of the drug,• The age before18,• Pregnancy and breastfeeding,• A history of pathology of tendons, which developed as a result of treatment with antibiotics hinolonovogo series • In preclinical and clinical studies after administration of moxifloxacin, there was a change in the electrophysiological parameters of the heart, manifested in the lengthening of the QT interval. In this regard, the use of moxifloxacin is contraindicated in patients in the following categories: congenital or documented acquired QT prolongation, electrolyte disturbances, especially neskorrigirovannoe hypokalaemia; clinically relevant bradycardia; clinically relevant heart failure with reduced ejection fraction of the left ventricle; a history of rhythm disturbance, accompanied by clinical symptoms.• Moxifloxacin cannot be used with other drugs, extension QT interval.• In connection with the presence in the composition of the drug is lactose, its intake is contraindicated in case of congenital lactose intolerance, lactase deficiency, glucose-galactose malabsorption.• Due to the limited number of clinical data, the use of moxifloxacin is contraindicated in patients with impaired liver function (class C classification for child-Pugh) and patients with the increase of transaminases more than five times the upper limit of normal.

Method of application and doses Adults It is recommended to take 1 tablet (400 mg) of moxifloxacin per day. The pills should be taken with liquid, squeezed enough water. The drug can be taken regardless of mealtime.The duration of therapy The duration of therapy tabletove form of the drug Avelox® depends on the type of infections.•exacerbation of chronic bronchitis – 5-10 days;•community-acquired pneumonia – 10 days;•acute bacterial sinusitis – 7 days;•inflammatory diseases of organs of small pelvis moderate and moderate to 14 days.According to clinical studies the duration of treatment tabletove form of the drug Avelox® up to 14 days.Step (intravenous, oral) therapyDuring clinical trials sequential therapy, most patients were switched from intravenous to oral way of administration of moxifloxacin for 4 days (community-acquired pneumonia) or 6 days (complicated infections of skin and subcutaneous tissues). The recommended total duration of treatment with tablets and solution for infusion, Avelox® is 7 - 14 days for negotia pneumonia and 7 - 21 days for complicated infections of skin and subcutaneous tissue. Exceed stated dose (400 mg 1 time per day) and duration of treatment for each indication is not recommended.Elderly patients and/or patients with low body weight dose adjustment for elderly patients/patients with low body weight do not need. The liverPatients with impaired hepatic function dose adjustment is not required (see section "peculiarities of use").Renal failure For patients with moderate renal insufficiency and moderate severity (including creatinine clearance < 30 ml/min/1.73 m2) and patients on continuous hemodialysis and prolonged outpatient peritoneal dialysis, dose adjustment is not required (see section "Pharmacological properties").

Children. Moxifloxacin is contraindicated in children (under 18 years). The efficacy and safety of moxifloxacin in children have not been established (see "Contraindications").

Overdose In case of accidental overdose not recommended any specific measures. In case of overdose should be guided by clinical and symptomatic supportive care and ECG monitoring in connection with the possibility of QT interval prolongation. The simultaneous use of activated charcoal with the dose of moxifloxacin 400 mg orally will reduce systemic availability of the drug by more than 80%. In case of overdose as the result of oral medication, the use of activated carbon at the initial stage of absorption may be effective in preventing the increase in systemic action of moxifloxacin.

Shelf life 5 years.

Storage conditions Store in the original package to protect from moisture at temperature not exceeding 25 °C, inaccessible for children place.

Packaging 5 tablets per blister; 1 blister in a cardboard box.

Manufacturer: Bayer Pharma AG, Germany.

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