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Troxevasin  gel 2% 100gr

Troxevasin gel 2% 100gr

Brand: Balkanpharma, Actavis
Product Code: 226
Availability: In Stock
Price: $17.00
Qty:     - OR -  
DELIVERY WITHIN 9-11 DAYS.
TROXEVASIN®
 
MANUAL for medical use of the drug
 
Composition:
 
active substance: troxerutin;
 
1 g of gel contains 20 mg troxerutin;
 
excipients: carbomer, triethanolamine, disodium salt of EDTA, benzalkonium chloride, purified water.
 

Dosage form. Gel 2 %.
 
Main physico-chemical properties: the gel from yellow to light brown color.
 

Pharmacotherapeutic group. Angioprotectors.
 
Code ATX С05С A04, collect statistical agencies.
 

The pharmacological properties.
 
Pharmacodynamics.
 
Troxevasin is a mixture of bioflavonoids containing not less than 95 % troxerutin. Troxerutin accumulates selectively in endotelialnogo layer venules, penetrates deep into subendothelial layer of the venous wall, and the concentration is higher than in the adjacent tissues. The drug prevents damage to cell membranes caused by arismendy.
 
The antioxidant effect is manifested in the reduction and elimination of the oxidizing properties of oxygen, inhibition of lipid peroxidation, protection of the vascular endothelium from oxidative action of hydroxyl radicals. Troxerutin reduces the increased capillary permeability and increases venous tone. Cytoprotective effect is in inhibition of the activation and adhesion of neutrophils, reducing the aggregation of red blood cells and increased resistance of erythrocytes to deformation, reducing the release of inflammatory mediators.
 
Increases venous-arterial reflux, lengthens time of re-filling of the venous, improves microcirculation and perfusion mcradio.
 
Action of Troxevazin aimed at reducing swelling, pain, improvement of trophism and elimination of various pathological disorders associated with venous insufficiency.
 
Pharmacokinetics. After local application Troksevazin gel the active ingredient is easily released from water soluble bases of the gel and penetrates into the dermis after about 30 minutes, and in the subcutaneous adipose tissue in 2-5 hours.
 

Clinical features.
 
Indications. Troxevasin gel is used for the symptomatic treatment of such diseases:
 
● venous insufficiency;
 
● predwarikozny and varicose syndrome;
 
● superficial thrombophlebitis, phlebitis and platlet condition;
 
● comprehensive treatment humoral disease;
 
● swelling and pain in trauma and varicose veins;
 
● muscle crump (sudane contraction of the calf muscles).

Contraindications. Hypersensitivity to troxerutin or any excipients of the drug. Troxevasin gel should not be applied to mucous membranes, open wounds and eczematous skin.

Interaction with other medicinal products and other forms of interaction. The drug enhances the effect of ascorbic acid on strengthening the structure and reducing the permeability of the vascular wall.

Features of the application.
 
Benzalkonium chloride included in the composition of the drug is an irritant and may cause skin reactions.
 
Patients with severe renal impairment is not recommended to use the drug for a long time.
 
If the use of the drug, the severity of symptoms is not reduced, consult a doctor.
 

Use during pregnancy or breast-feeding. There is no data relatively negative influence of the drug when used during pregnancy or breastfeeding.

The ability to influence the reaction rate when driving motor transport or operating other mechanisms. Not affected.

Method of application and doses.
 
The gel applied on the affected area evenly with a thin layer morning and evening, massaging with light massage movements until complete absorption of the drug. The gel has no smell and leaves no greasy stains on clothes. For more serious conditions it is recommended that combination therapy with capsules Troxevasin. In chronic venous insufficiency to apply a combined therapy until complete disappearance of symptoms.
 
The dosage and duration of drug administration is determined by the doctor, given the severity and course of the disease.

Children. There are no contraindications regarding the use of the drug in children.

Overdose. The local application of the cases of drug overdose not registered. In case of accidental ingestion of a large quantity of a drug it is necessary to take measures of elimination of the drug to provoke vomiting, to use means for the symptomatic treatment of. If necessary use in peritoneal dialysis.

Adverse reactions. When applying Troksevazin gel very rarely can be observed allergic reactions, including skin irritation, redness, itching, skin rash, dermatitis, angioedema. Usually these symptoms quickly disappear after drug discontinuation.
 
The expiration term. 5 years.

Storage conditions. Store in original container at temperature not exceeding 25 °C. Do not freeze! Keep out of reach of children.
 
Packing. 40 g or 100 g tubes. A tube in a cardboard box.
 
Manufacturer. Trojan-balkanfarma HELL/Balkanpharma-Troyan AD.

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