Instruction for use
Composition of the drug:
active substance: dymethyl sulfoxide;
1 vial contains dimethylsulfoxide 50 ml or 100 ml.
Dosage form. Liquid for external use.
Colorless liquid or colorless crystals. Hygroscopic.
The name and location of manufacturer.
Ukraine, 37500, Poltavskaya obl., Lubni, M., vul. Petrovsky, 16.
Means affecting the musculoskeletal system. Means that are applied topically for sore joints and muscles. ATC code M 02A X-03.
DMSO it penetrates through biological membranes, including the skin, has transport properties, contributing to the penetration through the skin medicines. Anti-inflammatory, analgesic, antiseptic, fibrinolytic action.
The application of the solution (90 %) Dimexidum on the skin it is undetectable in the blood after 5 min, reaching a maximum concentration after 4 - 6 hours with maintaining almost unchanged level for 1.5 - 3 days.
Dimethyl sulfoxide is excreted in urine and feces in unaltered form and in the form of dimethylsulfone.
Indications for use.
Inflammatory diseases of the musculoskeletal system (rheumatoid arthritis, ankylosing spondylitis, osteoarthritis deformans, arthropathy, sprain), for bruises, traumatic infiltrates, inflammatory edema, purulent wounds, abscesses, acute and chronic osteomyelitis, treatment of erythema nodosum, streptococcal.
Hypersensitivity to the drug. Severe cardiovascular failure, atherosclerosis, angina, stroke, coma, impaired renal function and liver, glaucoma, cataract. Pregnancy and breast-feeding. Children up to age 12 years.
Appropriate security measures when using.
The drug is used with caution in elderly patients.
To avoid the use of the drug if you are hypersensitive dimethyl sulfoxide is recommended that a tolerance test. The drug applied to the skin moistened with a cotton swab. Sharp hyperemia and itching are contraindications for future use Dimexidum.
To avoid getting the drug on mucous membranes and eyes. In case of contact with eyes, immediately wash out with running water.
Use during pregnancy or breast-feeding.
During pregnancy the drug is contraindicated.
If necessary, use of the drug during therapy is recommended to stop breast-feeding.
The ability to influence the rate of reaction at management of motor transport or operating other mechanisms.
The application of Dimexide can cause dizziness and weakness, so it is recommended to refrain from driving and other mechanisms.
Children under the age of 12 years the drug is not recommended.
Method of application and doses.
Dimexide is used externally, mostly in the form of aqueous solutions (30 - 50 % concentration) for compresses, swabs and washes. A compress should be applied on the affected areas, capturing the surrounding healthy skin.
In the treatment of erysipelas and ulcers the drug is used in the form of 30 - 50% aqueous solution 50 - 100 ml 2 - 3 times a day. Eczema, diffuse streptoderma recommended compresses with 40 - 90 % solution Dimexidum. When pustular skin diseases apply the 40 % solution. For local zaboly niya recommend 25 - 50 % solution of the drug for medical purposes in 100 - 150 ml 2 - 3 times a day. In the treatment of deep burns apply bandages with 20 - 30 % solution of Dimexidum (if necessary at a dose of 500 ml).
The duration of treatment in each case is determined by the doctor depending on the type and course of the disease.
Overdose of drug may cause allergic reactions (hives, swelling) and increase of side effects, which requires the appointment of antihistamines and discontinuation of the use Dimexidum.
Dimexide is generally well tolerated, but some patients may experience erythema, itching, dizziness, insomnia, weakness, dermatitis, diarrhea. In some cases, when bad portability Dimexidum, nausea, vomiting, bronchospasm. If you encounter these adverse reactions, discontinue the drug and consult a doctor.
Interaction with other medicinal products and other forms of interaction.
Dimexide enhances the action of ethanol (alcohol inhibits the excretion of the drug) and insulin (prolonged use of the drug, the dose of insulin reduce), acetyl salicylic acid, phenylbutazone, drugs, digitalis, quinidine, nitroglycerin, antibiotics (streptomycin, monomitsin), making the body insensitive to drugs for anesthesia.
Can be used along with heparin, antibacterial and non-steroidal anti-inflammatory drugs.
The expiration date.
The storage conditions.
Store protected from light and moisture place with a temperature of 15 °C to 25 °C.
Keep out of reach of children.
50 ml, 100 ml vials.