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Entrop 20 tablets 100mg

Entrop 20 tablets 100mg

Brand: OlainFarm, Latvia
Product Code: 435
Availability: In Stock
Price: $62.00
Qty:     - OR -  
DELIVERY WITHIN 9-11 DAYS.
ENTROP 
 
Description
 
 
General characteristics:
 
Chemical name: N-carbamoylmethyl-4-phenyl-2-pyrrolidone;
 
basic physical and chemical properties: white to white cream with a tint of color;
 
Composition: 1 tablet contains N-carbamoylmethyl-4-phenyl-2-pyrrole-dopamine 50 mg or 100 mg;
 
Excipients: potato starch, lactose, polyvinylpyrrolidone, sodium carboxymethyl starch, calcium stearate.
 
Form of release. Tablets.
 
Pharmacotherapeutic group. Psychostimulating and nootropic drugs.
 
PBX code N06B X.
 
Pharmacological properties.
 
Pharmacodynamics. Preparation with nootropic and cerebroprotective effect. Positively affects metabolism and blood circulation of the brain: stimulates oxidation-reduction processes, improves regional blood flow in ischemic regions of the brain, increases glucose utilization. Optimization of energy processes promotes increase of stability of the central nervous system to hypoxia and toxic factors. The drug improves learning processes, promotes consolidation of memory, restores and stabilizes the impaired integrative functions of the brain. Manifests moderate anxiolytic and sedative activity, weakening anxiety, fear, enhances and prolongs the effect of sleeping pills, narcotic and anti-parkinsonian drugs. Does not affect physical working capacity.
 
Pharmacokinetics. When taken orally, the drug is rapidly absorbed in the small intestine; Bioavailability is almost 100%. The maximum concentration in blood plasma is observed after 30 minutes after ingestion. The half-life is 4-5 hours. The drug does not bind to plasma proteins of the blood and is not metabolized in the body. Excreted mainly with urine in the unchanged form (95% of the dose taken for 30 h). The drug is well distributed in tissues, penetrates through the blood-brain barrier. The maximum concentration is observed in the cortex of the frontal, temporal and occipital lobes of the brain, as well as the cerebellum.
 
Indications for use. Cognitive disorders of the vascular, post traumatic and other genesis, involutional processes in the brain in the elderly, atherosclerosis of the vessels of the brain, parkinsonism, pathological processes with the phenomena of chronic cerebral circulation insufficiency, memory impairment, attention, speech. They are used in diseases of the nervous system with a decrease in intellectual and mental functions and violations of the emotional-volitional sphere; with viral neuroinfections to reduce ischemia and brain hypoxia, in the treatment of dementia, including Alzheimer's.
 
Method of administration and dose. The drug is prescribed individually.
 
The average single daily dose for adults is 150 mg (100-250 mg), the average daily dose is 250 mg (200-300 mg), the maximum daily dose for adults is 750 mg. Multiplicity of application - 1 - 2 times a day.
 
Daily dose of 100 mg taken once a day (in the morning), more than 100 mg - it is recommended to divide into 2 receptions. The course of treatment - from 2 weeks to 3 months, the average course of treatment - 30 days. If necessary, appoint a re-course of treatment in a month.
 
The drug is taken internally after a meal.
 
Side effect. The drug is usually well tolerated, but there may be signs of allergy (itching, rash), drowsiness, in the elderly - the increase in coronary insufficiency.
 
Contraindication. Hypersensitivity to the components of the drug; diabetes mellitus, renal failure; pregnancy and lactation; childhood
 
Overdose So far, cases of overdose have not been reported. If necessary, symptomatic therapy should be performed.
 
Application features. The drug is usually well tolerated.
 
Caution should be given to the drug in patients with severe organic liver damage and in kidney disease, severe hypertension, atherosclerosis; patients suffering panic attacks, acute psychotic conditions accompanied by psychomotor agitation.
 
Impact on the ability to drive vehicles and complex mechanisms.
 
When using the drug, you should refrain from driving vehicles and working with potentially dangerous mechanisms, as drowsiness, dizziness or other disturbances from the central nervous system may be observed.
 
Interaction with other medicinal products. The drug can exacerbate the effects of drugs that stimulate the central nervous system, antidepressants and nootropic drugs; intensifies and prolongs the effect of sleeping pills, narcotic and anti-parkinsonian drugs.
 
Terms and conditions of storage. Keep out of reach of children, dry, protected from light at a temperature of 15 ° C to 25 ° C.
 
Shelf life - 3 years.

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